Tuesday, 20 January 2009

Genetic Testing

This last century has seen an escalation in advancement of technology. In about one hundred years, man has gone from the horse and buggy to super sonic flight. These advancements have also been implanted in the health industry as seen in the almost doubling of the life expectancy of man.It also appears as though this escalation will only continue. One field where these advancements are moving at a very high speed is the field of genetics and biotechnology. The last ten years have seen some of the greatest landmarks in genetic genealogy research. The pattern in this field indicates that the discoveries and applications of those discoveries will continue to grow at an exponential rate.

With the increase in genetic knowledge there has also been an increase in the variety and ease of genetic testing available. Genetic testing refers to any sort of test which involves the study of the genome. When genetics was in its infancy, tests were expensive and took a long period of time to perform. Recent advances have significantly decreased the costs and time needed to perform genetic testing. This decrease in cost and time has made genetic testing available to more of the general public.

Genetic testing has also been used for determining family relationships. The simplest relationship to determine with a genetic test is a paternal or a maternal relationship. Today, genetic testing can also be used to determine other, more distant relationships. Genetic testing is available for full siblings, half siblings, grandparents and cousins. This allows family relationships to be determined even if one or more of the family members is deceased. As research continues, the ability to dive deeper into your family tree is becoming possible. With the use of Y-chromosome and mtDNA (mitochondrial DNA) testing more can be learned. The use of these genetic tests has allowed genealogists to verify their family trees and in some cases discover new branches that were not previously known. Genetic testing is even being used to understand the roots of family trees. This includes the use of genetic tests to look for Native American ancestry, and ancestry from different parts of Europe and Asia.

As knowledge and research in the area of genetics and biotechnology continue to advance, genetic testing will become even more accessible. This increase in use of genetic tests will give people more access to information. This information can be used to help solve crimes, increase the quality of health care, and provide information into your personal or family history.

Genetic Savings and Clone Forced to Shut Down

For the modest fee of only $50,000, grieving cat owners used to be able to have little Fluffy recreated. Alas, they will no longer have that option, at least for the time being.

The company that offered the cloning service, Genetic Savings and Clone, was launched in 2000 by billionaire and University of Phoenix founder John Sperling. Sperling had hoped to have his hunting dog Missy cloned, but scientists were never able to accomplish that feat. Nonetheless, Sperling decided to go into the business of trying to help others recreate their dearly departed pets.

Unfortunately, even for the most devoted of pet owners, there’s a limit to how much they’ll pay to have their dearly departed feline recreated. Genetic Savings and Clone’s hefty $50,000 price tag was just too much to generate much interest in their services. The company recently reduced the price to $32,000, but still there were no takers. The company sent letters to its customers last month letting them know that they will have to close at the end of the year. The letters said that Genetic Savings and Clone has been "unable to develop the technology to the point that cloning pets is commercially viable."

The company’s telephone answering system now contains a message saying that it is no longer taking orders, and it refers customers interested in having their pets’ genetic material frozen to ViaGen, Inc., a biotechnology company based in Austin, Texas.

The first cat that was cloned for commercial purposes was Little Nicky, who was requested by a woman in Texas who was saddened by the loss of her cat Nicky, who had died the previous year at age 17. Little Nicky was created from the original Nicky’s DNA, and cost the woman $50,000.

Since the company began, it was able to successfully clone five cats, but only two of them were sold to paying customers. Reproductive cycles of pets are too unpredictable for consistent and inexpensive cloning, according to Bonnie Beaver, past president of the American Veterinary Medical Association.

The ethical and scientific debate over cloning technology has become more and more heated since the sale of Little Nicky, with animal rights activists complaining that cloning cats isn’t necessary because there are thousands of stray cats euthanized each year because they don’t have homes. Those groups were thrilled to hear about Genetic Savings and Clones having to close its doors. Activists say that because cloning techniques are still primitive, the procedures fail more often than they succeed. "For every successful clone, dozens fail and die prematurely, have physical deformities, and face chronic pain and suffering," said Wayne Pacelle, head of the Humane Society of the United States.

Animal rights activists believe that cloning is at odds with basic animal welfare considerations. "It's no surprise the demand for cloned pets is basically nonexistent, and we're very pleased that Genetics Savings & Clone's attempt to run a cloning pet store was a spectacular flop," said Pacelle. "It's not just a bad business venture, but also an operation grounded on the misuse of animals."