Friday, 9 April 2010

Mesothelioma Cancer Prognosis

Generally, the most important variable in determining the prognosis and life expectancy of a patient mesothelioma cancer stage at diagnosis. Unfortunately, mesothelioma is more difficult to "stage" than other cancers. This is true for two reasons:

1) because its quite rare, and
2) because its initial symptoms are subtle, it is often advanced when diagnosed, it is difficult to stage.

Peritoneal mesothelioma in particular can be difficult to stage because, while pleural mesothelioma has multiple classification systems, pathologists have not yet developed a system of staging for peritoneal mesothelioma. Both pleural and peritoneal mesothelioma are very serious conditions and are not good prospects.

Since mesothelioma is usually diagnosed at an advanced stage, the statistics of five-year survival for early stage mesothelioma are generally unreliable. He also can not say with certainty which of the two types is a bad diagnostic peritoneal mesothelioma or pleural mesothelioma. Numerous studies show that peritoneal is more deadly and rapidly spreading mesothelioma pleural mesothelioma, but these studies are often contradicted by scholars who argue pleural mesothelioma is the most dangerous and difficult to deal with both. Usually, patients diagnosed with mesothelioma is peritoneal or pleural said they may have less than a year to live. However, according to researchers at major research centers around the world this is not necessarily the case. More recent studies indicate that patients with mesothelioma may, in some cases, have a better appearance than previously thought.

These studies suggest that about 10% of all mesothelioma patients will be alive 3 years later and about 5% will be alive 5 years later. However, if mesothelioma is detected early and treated, 50% survive 2 years and 20% of people survive 5 years.

In a clinical trial involving 120 patients with different types of pleural mesothelioma, all patients underwent pleural pneumonectomy (removal of the lung and pleura), followed by radiotherapy and chemotherapy. 45% were alive two years later and 20% were still alive five years later.

In the same study, patients with sarcomatoid and mixed mesothelioma was not as well. Only 20% of these patients were alive two years later, and none of them have survived five years.

However, patients who had no cancer in the lymph nodes and tumors of epithelioid type is much better. Nearly 75% survived more than two years and nearly 40% were alive after five years.

Another larger study conducted in Italy examined the records of 4.5 million people diagnosed with mesothelioma. The survival rates were as follows: 24% of people with pleural mesothelioma and 34% diagnosed with peritoneal mesothelioma were still alive one year after diagnosis. Two other important studies, in addition to examination of comparable populations, also revealed similar results.

Another variable that is extremely important for a patient is seeing his general health at the time of diagnosis. In general, the health of a patient, the better he or she will react to treatments against cancer, and the chances of longer survival. Doctor's have a method of classifying patients' health and to give each patient a score at diagnosis. This method of classification is called a patient's condition "performance" (PS). The best score is 0 and indicates a patient can normally take care of himself or with the help of. A performance index of 1 indicates that the patient can do things, but may need assistance. The more deteriorated health of the patient, the higher the number.

The patient must always keep in mind that statistics such as those mentioned here are by no means definitive. Survival has much to do with a number of different factors, including health, the type of mesothelioma, the choice of treatment, and even a moral patient. The statistics listed here are too general for patients to get an accurate idea of their own look.

Patients should consider taking part in clinical trials. Although nobody can say exactly why patients who are treated in clinical trials do better on average than those treated conventionally. Maybe with all the testing and monitoring that is done, patients become more confident that everything that can possibly be done is done.